SR9009, also known as stenoabolic, is a synthetic drug used to study circadian rhythms. It has been shown that it increases stamina, reduces anxiety and lowers cholesterol, weight and inflammation in mice. If this is confirmed in the human body, these effects will reproduce some useful effects of exercise on our body and, thus, improve our health. However, although supplements are provided online, they have not been tested in humans, and their side effects are still unknown. Read on to learn more about the SR9009.
Note. We do not recommend this drug by writing this article. Some of our readers who took the drug ask us to publish a message on it, and we provide only information presented in the scientific literature. Consult your doctor.
Introduction of SR9009
Our bodies work in a coordinated manner, with a 24-hour cycle, adapted for the rise and fall of the sun. This mode is called the circadian rhythm.
The circadian rhythm is supported by a circular mechanism that turns genes on and off (when the CLOCK and BMAL1 genes are turned on, they include PER and CRY, then PER / CRY turns off BMAL1 / CLOCK and resets the 24-hour cycle) [R].
REV-ERB is a pair of proteins that stabilize our internal clock by disabling BMAL1. In turn, they are activated by the heme group. Cheme is a small iron-containing compound that spreads throughout the body, for example, erythrocytes [R, R].
SR9009 is a compound that enhances the activity of REV-ERB (called agonist) and has good bioavailability [R].
Because of the many positive effects found in animals, the SR9009 found its way into the net and is sold and used as an add-on, mainly in the bodybuilding community. This is called “movement in the bottle.” However, we still have many things about this drug, including its side effects.
How SR9009 works
SR-9009 acts by increasing the amount of mitochondria in muscle tissue by activating and binding protein structures. Mitochondria are motility chambers in muscle cells that are places in which ATP is produced, which gives us energy for exercise and survival. Increasing the number of mitochondria in muscle cells can increase muscle strength and endurance. The study reported that SR-9009 increases energy production by 50%, which means that subjects can work longer at higher intensities (1).
Effect of SR9009
1) SR9009 can help lose weight
The mice injected with SR9009 for 7 days lost weight due to a decrease in fat mass. The consumption of food was not affected [R].
Similarly, obese mice injected with SR9009 for 30 days are 60% lighter than control animals. Triglycerides, total cholesterol, free fatty acids and insulin levels in the blood are also reduced [R].
In hereditary obese mice, SR9009 stopped weight gain after 12 days, without affecting glucose level or insulin resistance [R].
2) SR9009 can lower blood cholesterol levels
The introduction of SR9009 within 7-10 days reduced the levels of triglycerides and total cholesterol in the blood [R].
Genetically modified mice that tested a high cholesterol diet to produce a fat profile similar to humans received SR9009 for 8 weeks. The total level of cholesterol and triglycerides similarly decreases, whereas LDL cholesterol decreases, but HDL cholesterol does not affect [R].
3) SR9009 can improve stamina
Mice treated with SR9009 for 30 days showed increased endurance. They work longer and cover a much longer distance than the control [R].
So far, the human dose has not been established. Most experiments in mice use a dose of 100 mg / kg, administered intraperitoneally, that is, directly into the body cavity.
Nevertheless, the online bodybuilding forum recommends a much lower daily dose of 10-40 mg. They also recommend dividing it by 3-4 doses per day. Get more updates and latest SR9009 review from this blog.
There is no scientific report on the effectiveness of SR9009 when administered orally.